Collaborative Research

Joint Biotechnological Research with Osaka University

In order to further our contributions to society, Yoshindo decided to found a joint research course at Osaka University. We have sent employees to work on long-term research projects under the supervision of Professor Tadashi Wada at the Graduate School of Engineering. Our employees work tirelessly on core scientific research into nucleic acid drugs. In the future, we plan to set up a bio venture that works on the development of new drugs which can mark causal genes for specific illnesses.
This has garnered lots of attention as generic drug manufacturers rarely embark on these kinds of cutting-edge projects.


application number PCT / JP2015 / 086042
application year 2015
inventors Wada Tadashi,Watanabe Hajime,Takata Ryohei,Makado Gouki,Kitamura Ayaka
application number PCT / JP 2012 / 068085
application year 2012
inventors Wada Tadashi,Takeda Kei,Handa Hiroshi

Academic papers

A novel dual lock method for down-regulation of genes, in which a target mRNA is captured at 2 independent positions by linked locked nucleic acid antisense oligonucleotides

Takata Ryohei, Makado Gouki, Kitamura Ayaka, Watanabe Hajime, and Wada Tadashi.
RNA Biology

Antisense morpholino targeting just upstream from a poly(A) tail junction of maternal mRNA removes the tail and inhibits translation.

10.1093/nar/gks765, 1-10, 2012.
Wada Tadashi, Hara M, Taneda T, Qingfu C, Takata Ryohei, Moro K, Takeda Kei, Kishimoto T, and Handa Hiroshi.
Nucleic Acids Res.